Mac and Cheese Meatloaf

Featured in Reliable Main Course Recipes.

Combine savory meatloaf with creamy mac and cheese for a comforting dish that’s perfect for dinner. Start by mixing ground beef, crushed Ritz crackers, onion soup mix, and eggs, then top with a tangy ketchup-barbecue sauce blend. Bake until firm. Meanwhile, prepare macaroni blended with a smooth, cheesy sauce made of milk, cheddar soup, seasonings, and a shredded cheese mix. Once the meatloaf is done, layer the macaroni mixture on top, sprinkle with more cheese, and bake until golden and bubbly. Let cool before serving for a perfectly hearty meal.

Chef Zaho
Updated on Sat, 26 Apr 2025 01:56:03 GMT
A plate of food mac cheese meatloaf. Pin it
A plate of food mac cheese meatloaf. | alicesrecipes.com

This comforting mac and cheese meatloaf combines two family favorites into one incredible casserole that will have everyone asking for seconds. The savory meatloaf base topped with creamy macaroni and cheese creates a meal that satisfies all comfort food cravings in a single dish.

I started making this recipe when my children went through a phase of only wanting either meatloaf or mac and cheese for dinner. Rather than making two separate meals, I combined them into this casserole that has since become our most requested dinner for family gatherings.

Ingredients

  • Ketchup and Sweet Baby Ray's BBQ sauce: Create the perfect tangy glaze that caramelizes beautifully on top of the meatloaf
  • Lean ground beef: Provides a hearty base while minimizing excess grease
  • Ritz Crackers: Offer a buttery flavor and better texture than plain breadcrumbs
  • Lipton onion soup mix: Adds complex flavor without chopping onions
  • Eggs: Bind everything together ensuring the meatloaf holds its shape
  • Macaroni noodles: Cook to the perfect al dente texture that holds up well
  • Condensed cheddar cheese soup: Creates an ultra creamy sauce without making a roux
  • Shredded cheese blend: Combines the stretchy quality of mozzarella with sharp cheddar flavor
  • Seasonings: Garlic powder and onion powder enhance flavor without overwhelming

Step-by-Step Instructions

Prepare the sauce:
Mixing ketchup with Sweet Baby Ray's creates a perfect balance of tangy and sweet flavors that will caramelize beautifully on the meatloaf. This combination is what gives this dish its signature flavor profile that appeals to both kids and adults. Make sure to set aside half for topping the meatloaf before baking.
Create the meatloaf base:
The key to perfect meatloaf texture is gentle mixing. Combine the beef with crushed crackers, soup mix, eggs, and sauce just until incorporated. Overmixing will create a dense texture. Press the mixture into the baking dish with light pressure to create an even layer without compacting it too much.
Apply the sauce layer:
Spreading the remaining sauce mixture evenly across the top of the meatloaf creates a protective barrier that keeps the meat moist while baking. The sugars in the sauce will caramelize during baking, creating those delicious sticky edges everyone fights over.
Prepare the macaroni mixture:
Cook the pasta just until al dente as it will continue cooking in the oven. The secret to the creamiest mac and cheese is whisking the milk and cheese soup thoroughly before adding other ingredients. This ensures a smooth sauce without lumps.
Assemble and bake:
When layering the macaroni mixture on the partially baked meatloaf, pour it slowly and evenly across the entire surface. The generous amount of cheese on top creates that irresistible golden brown crust that makes this dish so appealing when it comes out of the oven.
A casserole dish filled with macaroni and meat. Pin it
A casserole dish filled with macaroni and meat. | alicesrecipes.com

The Ritz crackers are my secret ingredient in this recipe. I discovered their magic after running out of breadcrumbs one evening. The buttery flavor they impart to the meatloaf creates a richness that plain breadcrumbs simply cannot match. My grandmother actually called me after trying this recipe to ask what my secret was that made it taste so much better than her traditional version.

Make Ahead Options

This casserole is perfect for meal prepping. You can assemble the meatloaf portion up to 24 hours ahead and keep it refrigerated. When ready to cook, simply bake the meatloaf base for the initial 30 minutes, then proceed with the macaroni cheese topping. Alternatively, you can fully bake the entire casserole, cool completely, and refrigerate for up to 3 days. Reheat individual portions in the microwave or the entire casserole covered with foil in a 325°F oven until heated through.

Perfect Pairings

While this dish stands perfectly on its own as a complete meal, I love serving it with simple sides that complement its richness. A crisp green salad with a vinaigrette dressing provides the perfect contrast to the hearty casserole. Steamed green vegetables like broccoli or green beans also make excellent accompaniments. For special occasions, garlic bread or dinner rolls are wonderful for sopping up any extra sauce on your plate.

A white bowl with a casserole in it. Pin it
A white bowl with a casserole in it. | alicesrecipes.com

Customization Ideas

This recipe welcomes creative variations based on your family preferences. For a spicier version, add diced jalapeños or red pepper flakes to either the meatloaf or mac and cheese layers. You can substitute ground turkey for a lighter option, though I recommend adding a tablespoon of olive oil to maintain moisture. The cheese blend can be customized with pepper jack for heat, smoked gouda for depth, or extra sharp cheddar for more pronounced cheese flavor. Some of my friends even add a layer of sautéed mushrooms between the meatloaf and macaroni for an extra umami boost.

Frequently Asked Questions

→ Can I substitute the Ritz crackers in the meatloaf?

Yes, you can replace Ritz crackers with breadcrumbs, crushed pretzels, or even oats for a similar texture and binding effect.

→ What type of barbecue sauce works best?

A sweet and smoky barbecue sauce like Sweet Baby Ray’s Hickory & Brown Sugar is ideal, but you can choose any flavor that suits your taste.

→ How can I make this dish spicier?

Add some red pepper flakes or a dash of hot sauce to the meatloaf mix or cheese sauce for a spicy kick.

→ What other cheeses can I use for the macaroni layer?

Cheddar and mozzarella work great, but you can add gouda, Monterey Jack, or gruyere for a more complex flavor.

→ Can I prepare this dish ahead of time?

Yes, you can prep both the meatloaf and macaroni layers separately, store them in the fridge, and assemble and bake just before serving.

→ How do I know when the meatloaf is fully baked?

Use a meat thermometer to ensure the internal temperature of the meatloaf reaches 160°F (71°C) for safe consumption.

→ Can I use whole wheat pasta for the macaroni layer?

Yes, whole wheat pasta is a great alternative and adds a nutty flavor and extra fiber to the dish.

Mac and Cheese Meatloaf

Savor a hearty blend of cheesy macaroni and savory meatloaf in one delightful dish.

Prep Time
20 Minutes
Cook Time
50 Minutes
Total Time
70 Minutes
By: Fati Zaho

Category: Main Dishes

Difficulty: Intermediate

Cuisine: American

Yield: 8 Servings

Dietary: ~

Ingredients

→ Sauces

01 1 cup ketchup
02 1 cup Sweet Baby Ray’s Hickory & Brown Sugar barbecue sauce

→ Meatloaf base

03 2 lbs lean ground beef
04 30 Ritz Crackers, crushed
05 2 oz Lipton onion soup mix
06 2 eggs

→ Macaroni mixture

07 3 cups macaroni noodles
08 2 cups milk
09 10.5 oz condensed cheddar cheese soup
10 1 tsp salt
11 1 tsp pepper
12 1 tbsp garlic powder
13 1 tbsp onion powder
14 4 cups shredded mozzarella and cheddar cheese blend

Instructions

Step 01

Preheat the oven to 350°F (175°C). Grease a 9×13 inch baking dish.

Step 02

In a medium mixing bowl, combine the ketchup and barbecue sauce. Set aside.

Step 03

In a large mixing bowl, add the ground beef. Crush Ritz Crackers and add to the bowl. Add the Lipton onion soup mix and eggs, then pour in 1/2 cup of the ketchup and barbecue sauce mixture. Mix all ingredients together until fully combined.

Step 04

Press the mixture evenly into the prepared baking dish. Spread the remaining ketchup and barbecue sauce mixture on top. Bake for 30 minutes.

Step 05

Cook the macaroni noodles according to package directions, then drain.

Step 06

In a large bowl, whisk together milk and condensed cheddar cheese soup until smooth. Add salt, pepper, garlic powder, and onion powder. Stir in cooked macaroni and 2 cups of shredded cheese.

Step 07

Remove the meatloaf from the oven. Pour the macaroni mixture evenly on top. Sprinkle the remaining cheese over it. Bake for an additional 17-20 minutes, until the cheese is melted and starting to brown.

Step 08

Let the casserole sit for a few minutes before serving.

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Contains dairy
  • Contains gluten
  • Contains eggs

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 420
  • Total Fat: 20 g
  • Total Carbohydrate: 38 g
  • Protein: 23 g